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There is currently a lack of sustained release formulations for intra articular injection.The aim of this thesis was to produce and characterise an injectable intra articular drug delivery system capable of providing delivery of the steroid dexamethasone phosphate (DXMP) over 3 months. This would be an injectable hydrogel that contains drug loaded nanoparticles.Initially two systems Pluronic F127 gels and polyelectrolyte…

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Titan Mare Explorer. Image credit: NASA/JPLOne concept for a boat on Titan has already been proposed: the Titan Mare Explorer (TiME) would send a floating high tech buoy to land in a methane sea on this moon of Saturn to study its composition and its interaction with the atmosphere. But this Discovery class mission concept was nixed in favor of…

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Malaria is a parasitic disease that remains a global health burden. The ability of the parasite to rapidly develop resistance to therapeutics drives an urgent need for the delivery of new drugs. The Medicines for Malaria Venture have compounds known for their antimalarial ac tivity, but not necessarily the molecular targets. Drug dealers often lace their supply with fentanyl or…

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Besides normalizing blood fats, statin drugs such as Lipitor (atorvastatin) and Pravachol (pravastatin) also reduce inflammation, thus stabilizing any plaques in your coronary arteries and reducing the likelihood of their clotting. They have been shown to lower C RP by 15 to 25 percent. A recent study shows that high doses of statin drugs (80 milligrams of Lipitor) decreased C…

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“A person hunting, scouting his hunting area had found a human skull,” said Chief Deputy Jim Damante, with the Crawford County Sheriff’s Office. Monday, however Fort Smith determined the bones were in Crawford County. Crawford County deputies went out to the scene immediately, and Sheriff Brown said they worked on processing the area until it was dark.. Many people assume…

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“There are a few different schools of thought. I think there are many people [who] think that these bans are so extreme and would so clearly require the Supreme Court to confront the future of Roe v. Wade that the court will want to avoid taking one of these cases at least right now that it would rather maybe take…

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And so the clinics continue their march northward. The latest front line is Palm Beach County, just north of Broward County. That county had 372 suspected overdose deaths from legal pain pills in 2009, up from 248 in 2005, according to published reports. And Djukanovic, Ratko and Guo, Yike and Adcock, Ian M. And Chung, Kian FanRationale and objectives: Asthma…

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Data also showed Ganymede and Callisto may have a liquid saltwater layer. The biggest discovery surrounding Ganymede was the presence of a magnetic field. No other moon of any planet is known to have one.. Second, you don’t need to wash your bikini in laundry detergent, it’s too strong. Laundry detergents were manufactured to be so strong that it actually…

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Paul served several terms in Congress over the last few decades and has earned a reputation as a staunch conservative and self proclaimed of liberty. I am now proud to endorse his campaign for Lieutenant Governor. This current administration has even gone so far as to sue states they disagree with. Social changes in diasporic Chinese communities in the 21st…

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Cool colors can create a feeling of serene tranquility. Blues are often associated with rain, the sky, the ocean and water. Blues are said to be calming and suppress hunger and nightmares. Cupriavidus metallidurans CH34 displays resistance to a plethora of metals. Its response and underlying genetic determinants are dissected and detailed metal by metal (from arsenic to zinc). An…

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